MULTIPLEX RT-PCR | SEPSIS & BLOODSTREAM PATHOGENS

Genplex™ Blood Sepsis Panel with AMR

A comprehensive multiplex real-time PCR assay designed for rapid detection of clinically significant bloodstream pathogens and major antimicrobial resistance (AMR) genes directly from Whole Blood (EDTA). 44 targets in a single run — enabling targeted antimicrobial stewardship and rapid sepsis management decisions.

Sample: Whole Blood (EDTA) 44 Targets in One Run 11 AMR Resistance Genes Rapid Actionable Results
Order Information Key Features
Genplex™ Blood Sepsis Panel with AMR

Rapid Sepsis Diagnostics — 44 Targets, One Run

Sepsis is a medical emergency requiring rapid diagnostic intervention. Traditional blood culture methods take 24–72 hours to identify causative pathogens and resistance profiles, risking patient outcomes while empiric broad-spectrum antibiotics are administered.

The Genplex™ Blood Sepsis Panel with AMR delivers molecular identification of 44 key targets in hours, helping clinicians implement targeted, evidence-based antimicrobial therapy quickly — directly supporting antimicrobial stewardship programs.

The panel covers Gram-positive bacteria (12 targets), Gram-negative bacteria (15 targets), Yeast/Fungi (6 targets), and 11 AMR resistance genes including mecA, mecC, vanA, vanB, blaKPC, blaNDM, blaOXA-48, and more — all from a single Whole Blood (EDTA) specimen.

Key Specifications

  • Sample: Whole Blood (EDTA)
  • 44 total targets — Gram+, Gram−, Yeast, AMR
  • 12 Gram-Positive bacterial targets
  • 15 Gram-Negative bacterial targets
  • 6 Candida / Fungal targets
  • 11 Antimicrobial Resistance genes
  • Internal amplification/extraction control included

Key Highlights

Advanced molecular diagnostic capabilities engineered for clinical excellence and research-grade precision.

Rapid Results

Delivers bloodstream pathogen identification in hours, not days — optimizing time-to-treatment in critical sepsis conditions.

High Sensitivity & Specificity

Accurate identification directly from clinical specimen templates, reducing false positives and culture contamination concerns.

Comprehensive Panel Coverage

Simultaneously targets 44 clinically significant pathogens and resistance profiles in one reaction.

Actionable AMR Stewardship

11 AMR markers enable targeted antibiotic therapy selection and minimize empiric broad-spectrum antibiotic use.

Internal Control Included

Built-in internal amplification/extraction control ensures result validity in every run.

Comprehensive Pathotype Coverage

Gram-positives, Gram-negatives, Candida/Yeast, and AMR resistance genes all in one assay.

Detection Panel

Comprehensive multiplex detection covering a broad spectrum of clinically relevant pathogens and resistance markers.

Gram-Positive Bacteria (12)
  • Enterococcus spp.
  • Staphylococcus spp.
  • Staphylococcus aureus
  • Streptococcus spp.
  • Streptococcus agalactiae
  • Streptococcus pneumoniae
  • Streptococcus pyogenes
  • Listeria monocytogenes
  • Rickettsia spp.
  • Brucella spp.
  • Enterococcus faecalis
  • Enterococcus faecium
Gram-Negative Bacteria (15)
  • Acinetobacter calcoaceticus baumannii complex
  • Enterobacter cloacae complex
  • Escherichia coli
  • Klebsiella pneumoniae
  • Klebsiella oxytoca
  • Proteus mirabilis
  • Pseudomonas aeruginosa
  • Serratia marcescens
  • Neisseria meningitidis
  • Haemophilus influenzae
  • Salmonella typhi
  • Stenotrophomonas maltophilia
  • Morganella morganii
  • Citrobacter freundii
  • Leptospira spp.
Yeast / Fungal Pathogens (6)
  • Candida albicans
  • Candida glabrata
  • Candida tropicalis
  • Candida parapsilosis
  • Candida krusei
  • Aspergillus species
Antimicrobial Resistance Genes (11)
  • mecA
  • mecC
  • vanA
  • vanB
  • blaKPC
  • blaNDM
  • blaOXA-48
  • blaIMP
  • blaVIM
  • blaCTX-M
  • ESBL

Clinical Applications

Designed for diverse diagnostic and research use cases across the clinical spectrum.

Sepsis Emergency Management

Rapid identification of bloodstream pathogens in septic patients for early targeted antimicrobial therapy.

ICU & Critical Care

Comprehensive profiling of pathogens and AMR status in critically ill patients for improved outcomes.

Antimicrobial Stewardship Programs

Use AMR gene detection to guide antibiotic selection and reduce unnecessary broad-spectrum antibiotic use.

Post-Surgical Infection Screening

Screen post-operative patients for bloodstream infections and resistant organisms.

Technical Specifications

Parameter Value / Description
Sample Type Whole Blood (EDTA)
Total Targets 44 (Gram+, Gram−, Yeast, AMR)
Gram-Positive 12 bacterial targets
Gram-Negative 15 bacterial targets
Yeast/Fungi 6 targets
AMR Resistance Genes 11 targets (mecA, mecC, vanA, vanB, blaKPC, blaNDM, blaOXA-48, blaIMP, blaVIM, blaCTX-M, ESBL)
Internal Control Included
Intended Use In Vitro Diagnostic (IVD)
Storage -20°C

Ordering Information

For in vitro diagnostic use. Contact your regional distributor or ProbGen representative to place an order.

Product Name Cat. No. Pack Size
Genplex™ Blood Sepsis Panel with AMR GP1092 48 tests
Genplex™ Blood Sepsis Panel with AMR GP1093 96 tests

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Contact our scientific team for technical specifications, bulk pricing, or to request a demonstration of our diagnostics solutions.

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