IVDNGS™ Extended Transplant Panel (NGS)

IVDNGS™ Extended Transplant Panel (NGS)

Comprehensive NGS-Based Testing for Transplant Compatibility, Monitoring & Immune Profiling

The IVDNGS™ Extended Transplant Panel is a high-resolution, Next-Generation Sequencing (NGS) assay developed for accurate histocompatibility testing, immune monitoring, and post-transplant surveillance. Designed for in vitro diagnostic use, this panel enables precise HLA typing, donor-recipient matching, and detection of gene variants related to transplant rejection risks, infections, and immune complications.

It is suitable for solid organ and hematopoietic stem cell transplantation, ensuring improved outcomes through deeper genomic insight.

 Key Features

  • High-throughput NGS-based analysis of HLA Class I & II loci

  • Includes immune response genes, cytokines, drug metabolism markers

  • Detects SNPs, indels, and clinically relevant polymorphisms

  • Enables donor-recipient compatibility assessment

  • Supports monitoring of graft tolerance, rejection risk, and drug response

  • Developed under IVD compliance and ISO 13485 standards

Clinical Applications

  • Pre-transplant HLA typing & donor matching

  • Risk assessment of rejection & graft-versus-host disease (GVHD)

  • Post-transplant immune monitoring

  • Personalized immunosuppressive therapy selection

  • Research in transplant genomics and outcomes

Sample Requirements & Workflow

ParameterDetails
Sample TypeEDTA blood, buffy coat, saliva
DNA Input10–50 ng
Turnaround Time3–5 working days
OutputVariant report, HLA typing, CNV/SNP
CompatibilityIllumina NGS platforms